1: CGRP/CGRP Receptor Antibodies: Potential Adverse Effects Due to Blockade of Neovascularization?
Majima M, Ito Y, Hosono K, Amano H.
Trends Pharmacol Sci. 2019 Jan;40(1):11-21. doi: 10.1016/j.tips.2018.11.003. Epub 2018 Nov 28. Review. PMID: 30502971

1: Vascular endothelial growth factor receptor 1 (VEGFR1) tyrosine kinase signaling facilitates granulation tissue formation with recruitment of VEGFR1+ cells from bone marrow.
Park K, Amano H, Ito Y, Matsui Y, Kamata M, Yamazaki Y, Takeda A, Shibuya M, Majima M.
Anat Sci Int. 2018 Jun; 93(3): 372-383. doi: 10.1007/s12565-017-0424-8. Epub 2017 Dec 18. PMID: 29256114

2: Inhibition of microsomal prostaglandin E synthase-1 facilitates liver repair after hepatic injury in mice.
Nishizawa N, Ito Y, Eshima K, Ohkubo H, Kojo K, Inoue T, Raouf J, Jakobsson PJ, Uematsu S, Akira S, Narumiya S, Watanabe M, Majima M.
J Hepatol. 2018 Jul; 69(1): 110-120. doi: 10.1016/j.jhep.2018.02.009. Epub 2018 Feb 16. PMID: 29458169

3: RAMP1 in Kupffer cells is a critical regulator in immune-mediated hepatitis.
Inoue T, Ito Y, Nishizawa N, Eshima K, Kojo K, Otaka F, Betto T, Yamane S, Tsujikawa K, Koizumi W, Majima M.
PLoS One. 2018 Nov 21;13(11):e0200432. doi: 10.1371/journal.pone.0200432. eCollection 2018. PMID: 30462657

4. Vascular endothelial growth factor receptor 1 tyrosine kinase signaling facilitates healing of DSS-induced colitis by accumulation of Tregs in ulcer area.
Betto T, Amano H, Ito Y, Eshima K, Yoshida T, Matsui Y, Yamane S, Inoue T, Otaka F, Kobayashi K, Koizumi W, Shibuya M, Majima M.
Biomed Pharmacother. 2018 Dec 19;111:131-141. doi: 10.1016/j.biopha.2018.12.021. [Epub ahead of print]. PMID: 30579252

1: Angiotensin II subtype 1a receptor signaling in resident hepatic macrophages induces liver metastasis formation.
Shimizu Y, Amano H, Ito Y, Betto T, Yamane S, Inoue T, Nishizawa N, Matsui Y, Kamata M, Nakamura M, Kitasato H, Koizumi W, Majima M.
Cancer Sci., 2017 Sep; 108 (9): 1757-1768. doi: 10.1111/cas.13306. Epub 2017 Jul 27. PMID: 28660748

2: RAMP1 signaling improves lymphedema and promotes lymphangiogenesis in mice.
Mishima T, Ito Y, Nishizawa N, Amano H, Tsujikawa K, Miyaji K, Watanabe M, Majima M.
J Surg Res., 2017 Nov; 219: 50-60.. doi: 10.1016/j.jss.2017.05.124. Epub 2017 Jun 23. PMID: 29078910

1: Anti-tumor effects of interferon-beta cell therapy in murine model of melanoma.
Nakamura M, Kagawa L, Nakada N, Satoh M, Maehara S, Kojima F, Amano H, Murakumo Y, Iwabuchi K, Majima M, Kitasato H.
Int J Cancer Ther Oncol. 2016; 4(4): 4412-4422. DOI: 10.14319/ijcto.44.1227697638

2: Suppression of lymphangiogenesis by soluble vascular endothelial growth factor receptor-2 in a mouse lung cancer model.
Maehana S, Nakamura M, Ogawa F, Imai R, Murakami R, Kojima F, Majima M, Kitasato H.
Biomed Phamacother 2016.Dec;84:660-665. doi: 10.1016/j.biopha.2016.09.083. PMID: 27697638

3: Signaling of prostaglandin E receptors, EP3 and EP4 facilitates wound healing and lymphangiogenesis with enhanced recruitment of M2 macrophages in mice.
Hosono K, Isonaka R, Kawakami T, Narumiya S, Majima M.
PLoS One. 2016 Oct 6;11(10):e0162532. doi: 10.1371/journal.pone.0162532. PMID: 27711210

4: RAMP1 suppresses mucosal injury from dextran sodium sulfate-induced colitis in mice.
Kawashima-Takeda N, Ito Y, Nishizawa N, Kawashima R, Tanaka K, Tsujikawa K, Watanabe M, Majima M.
J Gastroenterol Hepatol. 2016 Aug 11. doi: 10.1111/jgh.13505. [Epub ahead of print] PMID: 27513455

5: BLT1 signaling protects the liver against acetaminophen hepatotoxicity by preventing excessive accumulation of hepatic neutrophis.
Kojo K, Ito Y, Eshima K, Nishizawa N, Ohkubo H, Yokomizo T, Shimizu T, Watanabe M, Majima M.
Sci Rep. 2016 Jul 11; 6: 29650. doi: 10.1038/srep29650. PMID: 27404729.

6: Thromboxane A synthase enhances blood flow recovery from hindlimb ischemia.
Amano H, Nakamura M, Ito Y, Kakutani H, Eshima K, Kitasato H, Narumiya S, Majima M.
J Surg Res 2016 Jul; 204 (1): 153-163. doi: 10.1016/j.jss.2016.04.011. Epub 2016 Apr 22. PMID: 27451882

7: Vascular endothelial growth factor receptor type 1 signaling prevents delayed wound healing in diabetes by attenuating the production of IL-1β by recruited macrophages.
Okizaki S, Ito Y, Hosono K, Oba K, Ohkubo H, Kojo K, Nishizawa N, Shibuya M, Majima M.
Am J Pathol 2016 Apr 13, pii: S0002-9440(16)30030-X, dol: 10. 1016/j.ajpath.2016.02.014. [Epub ahead of print]. PMID: 27085138.

8: Vascular endothelial growth factor receptor-1 (VEGFR-1) signaling enhances angiogenesis in a surgical sponge model.
Park K, Amano H, Ito Y, Kashiwagi S, Yamazaki Y, Takeda A, Shibuya M, Kitasato H, Majima M.
Biomed Phamacother 2016 Mar 78; 140-149. doi: 10. 1016/j, biopha. 2016.01.005. Epub 2016 Jan 25. PMID: 26898435.

1: PDGFRα plays a crucial role in connective tissue remodeling.
Horikawa S, Ishii Y, Hamashima T, Yamamoto S, Mori H, Fujimori T, Shen J, Inoue R, Nishizono H, Itoh H, Majima M, Abraham D, Miyawaki T, Sasahara M.
Sci Rep 2015 Dec 7; 5; 17948. doi: 10.1038/srep 17948. PMID: 26639755.

2: Roles of mPGES-1, an inducible prostaglandin E synthase, in enhancement of LPS-induced lymphangiogenesis in a mouse peritonitis model.
Matsuda H, Hosono K, Tsuru S, Kurashige C, Sekiguchi K, Akira S, Uematsu S, Okamoto H, Majima M..
Life Sci 2015 Dec 1; 142; 1-7. doi: 10.1016/j. lfs. 2015. 10. 008. Epub 2015 Oct 14. PMID: 26459051.

3: Hepatic stellate cells relay inflammation signaling from sinusoids to parenchyma in mouse models of immune-mediated hepatitis.
Fujita T., Soontrapa K., Ito y., Iwaisako K., Sagita Moniaga C., Asagiri M., Majima M., Narumiya S.
Hepatology 2015 Aug 6. doi: 10.1002/hep.28112. [Epub ahead of print]. PMID: 26248612.

4: The role of vascular endothelial growth factor receptor-1 signaling in the recovery from ischemia.
Amano H., Kato S. Ito Y., Eshima K., Ogawa F., Takahashi R. Sekiguchi K. Tamaki H., Sakagami H., Shibuya M., Majima M.
PLoS One 2015 Jul 2;10(7):e0131445. doi: 10.1371/journal.pone.0131445.

5: ThromboxaneA2 induces blood flow recovery via platelet adhesion to ischemic regions.
Amano H., Ito Y., Eshima K., Kato S., Ogawa F., Hosono K., Oba K., Tamaki H., Sakagami H., Shibuya M., Narumiya S., Majima M.
Cardiovascular Res. 2015 DOI: http://dx.doi.org/10.1093/cvr/cvv139 First published online: 2 May 2015. PMID: 25935870.

6: Adhesion of platelets through thromboxane A2 receptor signaling facilitates liver repair during acute chemical-induced hepatotoxicity.
Minamino T. Ito Y. Ohkubo H. Shimizu Y. Kojo K. Nishizawa N. Amano H. Narumiya S. Koizumi W, Majima M.
Life Sciences. 2015 Apr 25. pii: S0024-3205(15)00172-1. doi: 10.1016/j.lfs.2015.03.015. [Epub ahead of print] PMID: 25921763

7: Role of cyclooxygenase-2 in the development of interstitial fibrosis in kidneys following unilateral ureteral obstruction in mice.
Kamata M, Hosono K, Fujita T, Kamata K, Majima M.
Biomed Pharmacother. 2015 Mar;70:174-80. doi: 10.1016/j.biopha.2015.01.010. Epub 2015 Jan 15. PMID: 25776498

8: The role of vascular endothelial growth factor receptor-1 signaling in compensatory contralateral lung growth following unilateral pneumonectomy.
Matsui Y, Amano H, Ito Y, Eshima K, Tamaki H, Ogawa F, Iyoda A, Shibuya M, Kumagai Y, Satoh Y, Majima M.
Laboratory Investigation. 2015 Feb 2. doi: 10.1038/labinvest.2014.159. [Epub ahead of print] PMID: 25642830

1: Downregulation of the proangiogenic prostaglandin E receptor EP3 and reduced angiogenesis in a mouse model of diabetes mellitus.
Oba K, Hosono K, Amano H, Okizaki S, Ito Y, Shichiri M, Majima M.
Biomed Pharmacother. 2014 Oct;68(8):1125-33. doi: 10.1016/j.biopha.2014.10.022. Epub 2014 Oct 31. PMID: 25465154.

2: Suppressed recruitment of alternatively activated macrophages reduces TGF-β1 and impairs wound healing in streptozotocin-induced diabetic mice.
Okizaki S, Ito Y, Hosono K, Oba K, Ohkubo H, Amano H, Shichiri M, Majima M.
Biomed Pharmacother. 2014, Oct 31. pii: S0753-3322(14)00149-8. doi: 10.1016/j.biopha.2014.10.020. [Epub ahead of print] PMID: 25677561.

3: Renal (tissue) kallikrein-kinin system in the kidney and novel potential drugs for salt-sensitive hypertension.
Katori M, Majima M.
Prog Drug Res. 2014; 69: 59-109. PMID: 25130040

4: Prostanoid induces premetastatic niche in regional lymph nodes.
Ogawa F, Amano H, Eshima Y, Ito Y, Matsui Y, Hosono K, Kitasato H, Iyoda A, Iwabuchi K, Kumagai Y, Satoh Y, Narumiiya S, Majima M.
J. Clin. Invest. 2014 Nov 3;124(11):4882-94. doi: 10.1172/JCI73530. Epub 2014 Oct 1. PMID: 25271626

5: Clinical impact of lung age on postoperative readmission in non-small cell.
Ogawa F, Satoh Y, Iyoda A, Amano H, Kumagai Y, Majima M.
J. Surg. Res. 2014, Aug 30. pii: S0022-4804(14)00793-8. doi: 10.1016/j.jss.2014.08.028.[Epub ahead of print] PubMed PMID: 25255723.

6: VEGFR1-positive macrophages facilitate liver repair and sinusoidal reconstruction after hepatic ischemia/reperfusion injury.
Ohkubo H, Ito Y, Minamino T, Eshima K, Kojo K, Okizaki S, Hirata M, Shibuya M, Watanabe M, Majima M.
PLoS One 2014 Aug 27;9(8):e105533. doi: 10.1371/journal.pone.0105533. eCollection 2014. PMID: 25162491

7: Roles of receptor activity-modifying protein 1 in angiogenesis and lymphangiogenesis during skin wound healing in mice.
Kurashige C, Hosono K, Matsuda H, Tsujikawa K, Okamoto H, Majima M.
FASEB J. 2014 Mar;28(3):1237-47. doi: 10.1096/fj.13-238998. Epub 2013 Dec 5. PMID: 24308973

8: Vascular endothelial growth factor receptor 1 signaling facilitates gastric ulcer healing and angiogenesis through the up regulation of epidermal growth factor expression on VEGFR1+ CXCR4+ cells recruited from bone marrow.
Sato T, Amano H, Ito Y, Eshima K, Minamino T, Ae T, Katada C, Ohno T, Hosono K, Suzuki T, Shibuya M, Koizumi W, Majima M.
J Gastroenterol. 2014 Mar;49(3):455-69. doi: 10.1007/s00535-013-0869-z. Epub 2013 Aug 24. PMID: 23982810

9: Aspirin reduces lung cancer metastasis to regional lymph nodes.
Ogawa F, Amano H, Ito H, Matsui Y, Hosono K, Kitasato H, Satoh Y, Majima M.
Biomed Pharmacother. 2014 Feb;68(1):79-86. doi: 10.1016/j.biopha.2013.11.006. Epub 2013 Nov 26. PMID: 24331369

10: Roles of microsomal prostaglandin E synthase-1 in lung metastasis formation in prostate cancer RM9 cells.
Takahashi R, Amano H, Satoh T, Tabata K, Ikeda M, Kitasato H, Akira S, Iwamura M, Majima M.
Biomed Pharmacother. 2014 Feb;68(1):71-7. doi: 10.1016/j.biopha.2013.10.008. Epub 2013 Nov 8. PMID: 24291175

1: CXCR2-expressing myeloid-derived suppressor cells are essential to promote colitis-associated tumorigenesis.
Katoh H, Wang D, Daikoku T, Sun H, Dey SK, Dubois RN.
Cancer Cell. 2013 Nov;24(5):631-44. doi: 10.1016/j.ccr.2013.10.009. PMID: 24229710

2: A common polymorphism in the tissue kallikrein gene is associated with increased urinary excretions of calcium and sodium in Japanese volunteers.
Fujita T, Yasuda S, Kamata T, Kamata K, Kumagai Y, Majima M.
J Hum Genet. 2013 Sept 5. doi: 10.1038/jhg.2013.93. [Epub ahead of print] PMID: 24005896

3: NSAID, aspirin delays gastric ulcer healing with reduced accumulation of CXCR4+ VEGFR1+ cells to the ulcer granulation tissues.
Sato T, Amano H, Ito Y, Eshima K, Minamino T, Ae T, Katada C, Ohno T, Hosono K, Suzuki T, Shibuya M, Koizumi W, Majima M.
Biomed Pharmacother. 2013 Sep;67(7):607-613. doi: 10.1016/j.biopha.2013.01.009. Epub 2013 Jun 7. PMID: 23809370

4: [Lymphangiogenesis].
Hosono K, Majima M.
Nihon Yakurigaku Zasshi. 2013 May;141(5):290-1. Japanese. PMID: 23665561

5: Leukotriene B4 type-1 receptor signaling promotes liver repair after hepatic ischemia/reperfusion injury through the enhancement of macrophage recruitment.
Ohkubo H, Ito Y, Minamino T, Mishima T, Hirata M, Hosono K, Shibuya M, Yokomizo T, Shimizu T, Watanabe M, Majima M.
FASEB J. 2013 Aug;27(8):3132-43. doi: 10.1096/fj.13-227421. Epub 2013 Apr 29. PMID: 23629862

6: VEGF/VEGFR signaling in the liver repair from acetaminophen hepatotoxicity. (Mini Review)
Kato T, Ito Y, Majima M.
Inflammation and Regeneration. 2013 Jan; 33(1):66-71.

1: Angiotensin II type 1a signaling facilitates tumor metastasis formation through P-selectin-mediated interaction of tumor cells with platelets and endothelial cells.
Amano H, Ito Y, Ogawa F, Eshima K, Suzuki T, Oba K, Matsui Y, Kato S, Fukui T, Nakamura M, Kitasato H, Fukamizu A, Majima M.
Am J Pathol. 2013 Feb;182(2):553-64. doi: 10.1016/j.ajpath.2012.10.026. Epub 2012 Dec 3. PMID: 23219751

2: Tumor apoptosis in prostate cancer by PGD2 and its metabolite 15d-PGJ2 in murine model.
Nakamura M, Tsumura H, Satoh T, Matsumoto K, Maruyama H, Majima M, Kitasato H.
Biomed Pharmacother. 2013 Feb;67(1):66-71. doi: 10.1016/j.biopha.2012.10.012. Epub 2012 Nov 19. PMID: 23206752

3: Comparison of the effects of levofloxacin on QT/QTc interval assessed in both healthy Japanese and Caucasian subjects.
Sugiyama A, Nakamura Y, Nishimura S, Adachi-Akahane S, Kumagai Y, Gayed J, Naseem A, Ferber G, Taubel J, Camm J.
Br J Clin Pharmacol. 2012 Mar;73(3):455-9. PMID: 22442827

4: In vivo kinetics of indoxyl sulfate in humans and its renal interaction with angiotensin-converting enzyme inhibitor quinapril in rats.
Fujita T, Ishihara K, Yasuda S, Nakamura T, Maeda M, Kobayashi M, Sahashi K, Ikeda Y, Kumagai Y, Majima M.
J Pharmacol Exp Ther. 2012 Jun;341(3):626-33. doi: 10.1124/jpet.111.187732. Epub 2012 Mar 2. PMID: 22389425

5: Thromboxane A2 receptor signaling facilitates tumor colonization through P-selectin mediated interaction of platelets with tumor cells and endothelial cells.
Matsui Y, Amano H, Ito Y, Eshima K, Suzuki T, Ogawa F, Iyoda A, Satoh Y, Kato S, Nakamura M, Kitasato H, Narumiya S, Majima M.
Cancer Sci. 2012 Apr;103(4):700-7. doi: 10.1111/j.1349-7006.2012.02200.x. Epub 2012 Feb 2. PMID: 22296266

6: Thromboxane A2 receptor signaling promotes liver tissue repair after toxic injury through the enhancement of macrophage recruitment.
Minamino T, Ito Y, Ohkubo H, Hosono K, Suzuki T, Sato T, Ae T, Shibuya A, Sakagami H, Narumiya S, Koizumi W, Majima M.
Toxicol Appl Pharmacol. 2012 Feb 15;259(1):104-14. Epub 2011 Dec 21. PMID: 22206755

1: A randomized, double-blind, placebo-controlled, single-dose study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of denosumab administered subcutaneously to postmenopausal Japanese women.
Kumagai Y, Hasunuma Y, Padhi D.
Bone. 2011 Nov;49(5):1101-7. Epub 2011 Aug 12. PMID: 21871589

2: Identification of the rate-determining process in the hepatic clearance of atorvastatin in a clinical cassette microdosing study.
Maeda K, Ikeda Y, Fujita T, Yoshida K, Azuma Y, Haruyama Y, Yamane N, Kumagai Y, Sugiyama Y.
Clin Pharmacol Ther. 2011 Oct;90(4):575-81. doi: 10.1038/clpt.2011.142. Epub 2011 Aug 10. PMID: 21832990

3: Nonlinear pharmacokinetics of oral quindine and verapamil in healthy subjects: a clinical microdosing study.
Maeda K, Takano J, Ikeda Y, Fujita T, Oyama Y, Nozawa K, Kumagai Y, Sugiyama Y.
Clin Pharmacol Ther. 2011 Aug;90(2):263-70. doi: 10.1038/clpt.2011.108. Epub 2011 Jun 29. PMID: 21716273

4: Absence of adverse effects of oseltamivir on sleep: a double-blind, randomized study in healthy volunteers in Japan.
Uchimura N, Kuwahara H, Kumagai Y, Mishima K, Inoue Y, Rayner CR, Toovey S, Davies BE, Hosaka Y, Abe M, Prinssen EP.
Basic Clin Pharmacol Toxicol. 2011 Oct;109(4):309-14. doi: 10.1111/j.1742-7843.2011.00726.x. Epub 2011 Jun 29. PMID: 21592308

5: Application of a heat- and steam-generating sheet increases peripheral blood flow and induces parasympathetic predominance.
Nagashima Y, Igaki M, Suzuki A, Tsuchiya S, Yamazaki Y, Hishinuma M, Oh-Ishi S, Majima M.
Evid Based Complement Alternat Med. 2011;2011:965095. Epub 2011 Apr 26. PMID: 21584198

6: Role of COX-2 in lymphangiogenesis and restoration of lymphatic flow in secondary lymphedema.
Kashiwagi S, Hosono K, Suzuki T, Takeda A, Uchinuma E, Majima M.
Lab Invest. 2011 Sep;91(9):1314-25. doi: 10.1038/labinvest.2011.84. Epub 2011 May 16. PMID: 21577211

7: Phase I clinical study of NMK36: a new PET tracer with the synthetic amino acid analogue anti-[18F]FACBC.
Asano Y, Inoue Y, Ikeda Y, Kikuchi K, Hara T, Taguchi C, Tokushige T, Maruo H, Takeda T, Nakamura T, Fujita T, Kumagai Y, Hayakawa K.
Ann Nucl Med. 2011 Jul;25(6):414-8. Epub 2011 Mar 16. PMID: 21409348

8: EP3/EP4 signaling regulates tumor microenvironment formation by bone marrow-derived fibroblasts. (Mini Review)
Katoh H, Hosono K, Suzuki T, Watanabe M, Majima M.
Inflammation and Regeneration. 2011 May;31(3):316-324.

9: Roles of calcitonin gene-related peptide in enhancement of angiogenesis. (Review Article)
Majima M, Toda M, Ito I, Ohno T, Mishima T, Suzuki T, Hosono K, Hayashi I.
Inflammation and Regeneration. 2011 March;31(2):146-150.

10: Anti-tumor effects of prostaglandin D2 and its metabolites, 15-deoxy-Δ12, 14-PGJ2, by peroxisome proliferator-activated receptor (PPAR) γ-dependent and -independent pathways. (Mini Review)
Nakamura M, Yamaguchi S, Motoyoshi K, Negishi M, Saiti-Taki T, Matsumoto K, Hayashi I, Majima M, Kitasato H.
Inflammation and Regeneration. 2011 March;31(2):189-195.

11: Microsomal prostaglandin E synthase-1enhances bone cancer growth and bone cancer-related pain behaviors in mice.
Isono M, Suzuki T, Hosono K, Hayashi I, Sakagami H, Uematsu S, Akira S, Declerck YA, Okamoto H, Majima M.
Life Sci. 2011 Apr;88(15-16):693-700. Epub 2011 Feb 12. PMID: 21324324

12: Roles of prostaglandin E2-EP3/EP4 receptor signaling in the enhancement of lymphangiogenesis during fibroblast growth factor-2-induced granulation formation.
Hosono K, Suzuki T, Tamaki H, Sakagami H, Hayashi I, Narumiya S, Alitalo K, Majima M.
Arterioscler Thromb Vasc Biol. 2011 May;31(5):1049-58. Epub 2011 Feb 10. PMID: 21311040

1: The inducible prostaglandin E synthase mPGES-1 regulates growth of endometrial tissues and angiogenesis in a mouse implantation model.
Numao A, Hosono K, Suzuki T, Hayashi I, Uematsu S, Akira S, Ogino Y, Kawauchi H, Unno N, Majima M.
Biomed Pharmacother. 2011 Feb;65(1):77-84. Epub 2010 Dec 30. PMID: 21247731

2: Vascular endothelial growth factor receptor-1 signaling promotes liver repair through restoration of liver microvasculature after acetaminophen hepatotoxicity.
Kato T, Ito Y, Hosono K, Suzuki T, Tamaki H, Minamino T, Kato S, Sakagami H, Shibuya M, Majima M.
Toxicol Sci. 2011 Mar;120(1):218-29. Epub 2010 Dec 6. PMID: 21135413

3: Calcitonin gene-related peptide facilitates revascularization during hindlimb ischemia in mice.
Mishima T, Ito Y, Hosono K, Tamura Y, Uchida Y, Hirata M, Suzuki T, Amano H, Kato S, Kurihara Y, Kurihara H, Hayashi I, Watanabe M, Majima M.
Am J Physiol Heart Circ Physiol. 2011 Feb;300(2):H431-9. Epub 2010 Dec 3. PubMed PMID: 21131474

4: Role of microsomal prostaglandin E synthase-1 in the facilitation of angiogenesis and the healing of gastric ulcers.
Ae T, Ohno T, Hattori Y, Suzuki T, Hosono K, Minamino T, Sato T, Uematsu S, Akira S, Koizumi W, Majima M.
Am J Physiol Gastrointest Liver Physiol. 2010 Nov;299(5):G1139-46. Epub 2010 Sep 2. PMID: 20813913

5: Roles of prostaglandin E2-EP1 receptor signaling in regulation of gastric motor activity and emptying.
Mizuguchi S, Ohno T, Hattori Y, Ae T, Minamino T, Satoh T, Arai K, Saeki T, Hayashi I, Sugimoto Y, Narumiya S, Saigenji K, Majima M.
Am J Physiol Gastrointest Liver Physiol. 2010 Nov;299(5):G1078-86. Epub 2010 Aug 26. PMID: 20798358

6: Microdose study of a P-glycoprotein substrate, fexofenadine, using a non-radioisotope-labelled drug and LC/MS/MS.
Yamazaki A, Kumagai Y, Yamane N, Tozuka Z, Sugiyama Y, Fujita T, Yokota S, Maeda M.
J Clin Pharm Ther. 2010 Apr;35(2):169-75. PMID: 20456735

7: mPGES-1-expressing bone marrow-derived cells enhance tumor growth and angiogenesis in mice.
Kamata H, Hosono K, Suzuki T, Ogawa Y, Kubo H, Katoh H, Ito Y, Uematsu S, Akira S, Watanabe M, Majima M.
Biomed Pharmacother. 2010 Jul;64(6):409-16. Epub 2010 Feb 25. PMID: 20452172

8: Effect of erythropoietin on angiogenesis with the increased adhesion of platelets to the microvessels in the hind-limb ischemia model in mice.
Kato S, Amano H, Ito Y, Eshima K, Aoyama N, Tamaki H, Sakagami H, Satoh Y, Izumi T, Majima M.
J Pharmacol Sci. 2010 Feb;112(2):167-75. Epub 2010 Feb 4. PMID: 20134117

9: COX-2 and prostaglandin EP3/EP4 signaling regulate the tumor stromal proangiogenic microenvironment via CXCL12-CXCR4 chemokine systems.
Katoh H, Hosono K, Ito Y, Suzuki T, Ogawa Y, Kubo H, Kamata H, Mishima T, Tamaki H, Sakagami H, Sugimoto Y, Narumiya S, Watanabe M, Majima M.
Am J Pathol. 2010 Mar;176(3):1469-83. Epub 2010 Jan 28. PubMed PMID: 20110411

1: Host prostaglandin EP3 receptor signaling relevant to tumor-associated lymphangiogenesis.
Kubo H, Hosono K, Suzuki T, Ogawa Y, Kato H, Kamata H, Ito Y, Amano H, Kato T, Sakagami H, Hayashi I, Sugimoto Y, Narumiya S, Watanabe M, Majima M.
Biomed Pharmacother. 2010 Feb;64(2):101-6. Epub 2009 Oct 20. PMID: 20034758

2: Recruited bone marrow cells expressing the EP3 prostaglandin E receptor subtype enhance angiogenesis during chronic inflammation.
Ueno T, Suzuki T, Oikawa A, Hosono K, Kosaka Y, Amano H, Kitasato H, Toda M, Hayashi I, Kato T, Ito Y, Sugimoto Y, Narumiya S, Okamoto H, Majima M.
Biomed Pharmacother. 2010 Feb;64(2):93-100. Epub 2009 Oct 17. PMID: 20015609

3: Estimating the contribution of genes to variation in renal drug clearance by active secretion using multiple data from clinical phase I studies.
Fujita T, Kumagai Y, Nakahara I, Ohtani Y, Majima M.
J Clin Pharmacol. 2010 Jan;50(1):109-14. Epub 2009 Nov 6. PMID: 19897765

4: Microsomal prostaglandin E synthase-1in both cancer cells and hosts contributes to tumour growth, invasion and metastasis.
Kamei D, Murakami M, Sasaki Y, Nakatani Y, Majima M, Ishikawa Y, Ishii T, Uematsu S, Akira S, Hara S, Kudo I.
Biochem J. 2009 Dec 23;425(2):361-71. PMID: 19845504

5: Roles of a prostaglandin E-type receptor, EP3, in upregulation of matrix metalloproteinase-9 and vascular endothelial growth factor during enhancement of tumor metastasis.
Amano H, Ito Y, Suzuki T, Kato S, Matsui Y, Ogawa F, Murata T, Sugimoto Y, Senior R, Kitasato H, Hayashi I, Satoh Y, Narumiya S, Majima M.
Cancer Sci. 2009 Dec;100(12):2318-24. Epub 2009 Aug 25. PMID: 19799610

6: Reduced angiogenesis and delay in wound healing in angiotensin II type 1a receptor-deficient mice.
Kurosaka M, Suzuki T, Hosono K, Kamata Y, Fukamizu A, Kitasato H, Fujita Y, Majima M.
Biomed Pharmacother. 2009 Nov;63(9):627-34. Epub 2009 Feb 14. PMID: 19464844

7: Bone marrow-derived EP3-expressing stromal cells enhance tumor-associated angiogenesis and tumor growth.
Ogawa Y, Suzuki T, Oikawa A, Hosono K, Kubo H, Amano H, Ito Y, Kitasato H, Hayashi I, Kato T, Sugimoto Y, Narumiya S, Watanabe M, Majima M.
Biochem Biophys Res Commun. 2009 May 15;382(4):720-5. Epub 2009 Mar 24. PMID: 19318087

8: An ATP-sensitive potassium channel blocker suppresses sodium-induced hypertension through increased secretion of urinary kallikrein.
Kamata Y, Fujita T, Kato T, Hayashi I, Kurosaka M, Katori M, Fujita Y, Majima M.
Hypertens Res. 2009 Mar;32(3):220-6. PMID: 19262486

9: Safety, tolerability and pharmacokinetics of TAS-108, a novel anti-oestrogen, in healthy post-menopausal Japanese women: a phase I single oral dose study.
Kumagai Y, Fujita T, Ozaki M, Yokota S, Maeda M, Shida M, Otani Y, Yamaya H, Tsuruta H.
Basic Clin Pharmacol Toxicol. 2009 May;104(5):352-9. PMID: 19175362

1: TNF-alpha induces thromboxane receptor signaling-dependent microcirculatory dysfunction in mouse liver.
Katagiri H, Ito Y, Ito S, Murata T, Yukihiko S, Narumiya S, Watanabe M, Majima M.
Shock. 2008 Oct;30(4):463-7. PMID: 18800000

2: Are all individuals equally sensitive in the blood pressure to high salt intake? (Review Article).
Katori M, Majima M.
Acta Physiol Hung. 2008 Sep;95(3):247-65. Review. PMID: 18788465

3: Neuronal system-dependent facilitation of tumor angiogenesis and tumor growth by calcitonin gene-related peptide.
Toda M, Suzuki T, Hosono K, Hayashi I, Hashiba S, Onuma Y, Amano H, Kurihara Y, Kurihara H, Okamoto H, Hoka S, Majima M.
Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13550-5. Epub 2008 Aug 29. PMID: 18757746

4: Contribution of down-regulation of intestinal and hepatic cytochrome P450 3A to increased absorption of cyclosporine A in a rat nephrosis model.
Fujita T, Yasuda S, Kamata Y, Fujita K, Ohtani Y, Kumagai Y, Majima M.
J Pharmacol Exp There. 2008 Nov;327(2):592-9. Epub 2008 Aug 25. PMID: 18725544

5: Blockade of an angiotensin type I receptor enhances effects of radiation on tumor growth and tumor-associated angiogenesis by reducing vascular endothelial growth factor expression.
Ohnuma Y, Toda M, Fujita M, Hosono K, Suzuki T, Ogawa Y, Amano H, Kitasato H, Hayakawa K, Majima M.
Biomed Pharmacother. 2009 Feb;63(2):136-45. Epub 2007 Dec 26. PMID: 18691848

6: Effects of inhaled monoethanolamine on bronchoconstriction.
Kamijo Y, Hayashi I, Ide A, Yoshimura K, Soma K, Majima M.
J Appl Toxicol. 2009 Jan;29(1):15-9. PMID: 18651722

7: Roles of calcitonin gene-related peptide in facilitation of wound healing and angiogenesis.
Toda M, Suzuki T, Hosono K, Kurihara Y, Kurihara H, Hayashi I, Kitasato H, Hoka S, Majima M.
Biomed Pharmacother. 2008 Jul-Aug;62(6):352-9. Epub 2008 Mar 6. PMID: 18430544.

8: A role of the renal kallikrein-kinin system in the kidney.
Katori M, Majima M.
Acta Physiol Hung. 2008 Mar;95(1):127-8; author reply 129-30. PMID: 18390005

9: Tumor necrosis factor-alpha induces thromboxane receptor signaling-dependent microcirculatory dysfunction in mouse liver.
Katagiri H, Ito Y, Ito S, Murata T, Narumiya S, Watanabe M, Majima M.
Shock. 2008 Feb 21. [Epub ahead of print] PMID: 18323744

10: A novel model of pain sensation using superfused gastrosplenic omentum preparation of anesthetized rats.
Yang SJ, Katori M, Majima M.
J Pharmacol Sci. 2008 Feb;106(2):249-56. Epub 2008 Feb 9. PMID: 18270472

11: Roles of calcitonin gene-related peptide in maintenance of gastric mucosal integrity and in enhancement of ulcer healing and angiogenesis.
Ohno T, Hattori Y, Komine R, Ae T, Mizuguchi S, Arai K, Saeki T, Suzuki T, Hosono K, Hayashi I, Oh-Hashi Y, Kurihara Y, Kurihara H, Amagase K, Okabe S, Saigenji K, Majima M.
Gastroenterology. 2008 Jan;134(1):215-25. Epub 2007 Oct 5. PMID: 18054007

12: Leukotriene B4/leukotriene B4 receptor pathway is involved in hepatic microcirculatory dysfunction elicited by endotoxin.
Ito S, Ito Y, Katagiri H, Suzuki T, Hoka S, Yokomizo T, Shimizu T, Majima M.
Shock. 2008 Jul;30(1):87-91. PMID: 18004232

13: Gastric mucosal protection against ethanol by EP2 and EP4 signaling through the inhibition of leukotriene C4 production.
Hattori Y, Ohno T, Ae T, Saeki T, Arai K, Mizuguchi S, Saigenji K, Majima M.
Am J Physiol Gastrointest Liver Physiol. 2008 Jan;294(1):G80-7. Epub 2007 Oct 18. PMID: 17947453